Free Article Access: Wiley Interscience

"These contributions provide insight into current areas of debate in the field of inflammation and immunology. In particular, they highlight current interest in the interface between innate and adaptive immunity and present intriguing prospects for future therapeutic developments in a variety of disease areas. We should not forget that infectious disease is a huge burden on humanity and the defensive systems of the specific and non-specific immune systems deserve our full attention. We hope that this series of reviews is both timely and useful, stimulating new thought and research in this key area of pathology."

• The role of TLR activation in inflammation
• Nod-like proteins in inflammation and disease
• TNF-mediated inflammatory disease
• Macrophage activation by endogenous danger signals
• Control of apoptosis in autoimmunity
• The highway code of T cell trafficking
• Cellular and molecular mechanisms of fibrosis
• The immunology of sepsis
• IL-10 and the resolution of infections
• Immune activation and inflammation in HIV-1 infection: causes and consequences
• Innate and adaptive mechanisms to control of pathological intestinal inflammation
• Innate immunity in inflammatory bowel disease: a disease hypothesis
• Stress proteins in CNS inflammation
• The role of natural killer T cells in lung inflammation